A gut feeling for obesity: 7TM sensors on enteroendocrine cells
- PMID: 19041758
- DOI: 10.1016/j.cmet.2008.11.004
A gut feeling for obesity: 7TM sensors on enteroendocrine cells
Abstract
Enteroendocrine cells, which secrete peptide hormones in response to sensation of food and gut microbiota products, can now be genetically tagged, isolated, cultured, and characterized for expression of the elusive chemosensors, as shown in publications in PNAS (Samuel et al., 2008) and in this issue (Reimann et al., 2008).
Comment on
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Glucose sensing in L cells: a primary cell study.Cell Metab. 2008 Dec;8(6):532-9. doi: 10.1016/j.cmet.2008.11.002. Cell Metab. 2008. PMID: 19041768 Free PMC article.
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