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Review
. 2008 Dec 4;3(6):583-6.
doi: 10.1016/j.stem.2008.11.002.

Overcoming obstacles in the search for the site of hematopoietic stem cell emergence

Momoko Yoshimoto  1 , Prashanth Porayette, Mervin C Yoder
Affiliations
Review

Overcoming obstacles in the search for the site of hematopoietic stem cell emergence

Momoko Yoshimoto et al. Cell Stem Cell. .

Abstract

The murine embryo has become a valuable tool to examine the ontogeny of hematopoiesis. However, the onset of the systemic circulation has long been a confounding developmental variable that may mask the site of blood cell emergence. This Minireview examines some approaches that have been applied to overcome this obstacle.

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