A TRP channel-steroid marriage
- PMID: 19043430
- DOI: 10.1038/ncb1208-1383
A TRP channel-steroid marriage
Abstract
A surprising functional association between TRPM3, a mysterious member of the family of transient receptor potential (TRP) cation channels, and the sulphated version of pregnenolone, 'mother' of all steroid hormones, has been identified.
Comment on
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Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells.Nat Cell Biol. 2008 Dec;10(12):1421-30. doi: 10.1038/ncb1801. Epub 2008 Nov 2. Nat Cell Biol. 2008. PMID: 18978782
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