Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Aug;4(4):723-30.
doi: 10.2147/ndt.s1450.

Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents

Roberto Canitano  1 , Valeria Scandurra
Affiliations

Risperidone in the treatment of behavioral disorders associated with autism in children and adolescents

Roberto Canitano et al. Neuropsychiatr Dis Treat. 2008 Aug.

Abstract

This is a review of the clinical trials investigating the efficacy and safety of risperidone in the treatment of children with autistic spectrum disorders (ASD). The main clinical characteristics are impairment in social skills, communication difficulties, repetitive movements and behaviors, including stereotypies. Pharmacotherapy is mainly directed at the so-called target symptoms, ie, behavioral disorders and the various kinds of repetitions associated with ASD. According to the available data, risperidone seems to be moderately efficacious and safe for treating behavioral disorders. 4 double blind controlled trial. 3 reanalysis studies, and 12 open studies have documented the role of risperidone in children with ASD. Controlled studies have been thoroughly considered in this review.

Keywords: autism; pervasive developmental disorders; risperidone.

PubMed Disclaimer

References

    1. Anderson GM, Scahill L, McCracken JT, et al. Effects of short- and long-term risperidone treatment on prolactin levels in children with autism. Biol Psychiatry. 2007;61:545–50. - PubMed
    1. Aman MG. Management of hyperactivity and other acting-out problems in patients with autism spectrum disorder. Semin Pediatr Neurol. 2004;11:225–8. - PubMed
    1. Aman MG, Singh NN, Stewart AW, et al. The aberrant behavior checklist: A behavior rating scale for the assessment of treatment effects. Am J Ment Defic. 1985;89:485–91. - PubMed
    1. Aman MG, Tassé MJ, Rojahn J, et al. The Nisonger CBRF: A child behavior rating form for children with developmental disabilities. Res Dev Disabil. 1996;17:41–57. - PubMed
    1. [APA] American Psychiatric Association. Diagnostic and Statistic Manual of Mental Disorders. 4. Washington, DC: American Psychiatric Association; 1994. Pervasive developmental disorders.

LinkOut - more resources