Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008;12(6):R152.
doi: 10.1186/cc7141. Epub 2008 Dec 1.

Sedation practice in the intensive care unit: a UK national survey

Affiliations

Sedation practice in the intensive care unit: a UK national survey

Henrik Reschreiter et al. Crit Care. 2008.

Abstract

Introduction: The purpose of this study was to evaluate sedation practice in UK intensive care units (ICUs), particularly the implementation of daily sedation holding, written sedation guidelines, sedation scoring tools and choice of agents.

Methods: A national postal survey was conducted in all UK ICUs.

Results: A total of 192 responses out of 302 addressed units were received (63.5%). Of the responding ICUs, 88% used a sedation scoring tool, most frequently the Ramsey Sedation Scale score (66.4%). The majority of units have a written sedation guideline (80%), and 78% state that daily sedation holding is practiced. A wide variety of sedating agents is used, with the choice of agent largely determined by the duration of action rather than cost. The most frequently used agents were propofol and alfentanil for short-term sedation; propofol, midazolam and morphine for longer sedation; and propofol for weaning purposes.

Conclusions: Most UK ICUs use a sedation guideline and sedation scoring tool. The concept of sedation holding has been implemented in the majority of units, and most ICUs have a written sedation guideline.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Importance of cost and duration of action on choice of agent. A total of 185 units are included in this analysis. VAS, visual analogue scale (range: 0 = not important to 10 = most important).

References

    1. Hansen-Flaschen JH, Brazinsky S, Basile C, Lanken PN. Use of sedating drugs and neuromuscular blocking agents in patients requiring mechanical ventilation for respiratory failure. A national survey. Jama. 1991;266:2870–2875. - PubMed
    1. Roth-Isigkeit A, Brechmann J, Dibbelt L, Sievers HH, Raasch W, Schmucker P. Persistent endocrine stress response in patients undergoing cardiac surgery. J Endocrinol Invest. 1998;21:12–19. - PubMed
    1. Lewis KS, Whipple JK, Michael KA, Quebbeman EJ. Effect of analgesic treatment on the physiological consequences of acute pain. Am J Hosp Pharm. 1994;51:1539–1554. - PubMed
    1. Schelling G. Post-traumatic stress disorder in somatic disease: lessons from critically ill patients. Prog Brain Res. 2008;167:229–237. - PubMed
    1. Burns AM, Shelly MP, Park GR. The use of sedative agents in critically ill patients. Drugs. 1992;43:507–515. - PubMed

MeSH terms