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. 2009 Jun;33(3):757-60.
doi: 10.1007/s00264-008-0700-2. Epub 2008 Dec 3.

Survival of massive allografts in segmental oncological bone defect reconstructions

P H J Bullens  1 , N M Minderhoud, M C de Waal Malefijt, R P H Veth, P Buma, H W B Schreuder
Affiliations

Survival of massive allografts in segmental oncological bone defect reconstructions

P H J Bullens et al. Int Orthop. 2009 Jun.

Abstract
in English, French

Reconstructions of large segmental bone defects after resection of bone tumours with massive structural allografts have a high number of reported complications including fracture, infection and non-union. Our goal is to report the survival and complications of massive allografts in our patients. A total of 32 patients were evaluated for fracture, infection, non-union rate and survival of their massive allograft reconstructions. The average follow-up for this group was five years and three months. The total fracture rate was 13% with a total infection rate of 16%. We found a low union rate of 25%. The total survival of the allografts was 80.8% (+/- 18.7%) after five years. We found a five-year allograft survival of 80.8% which is comparable with other studies.

La reconstruction des larges pertes de substances osseuses après la résection des tumeurs osseuses par des allogreffes structurales est pourvoyeuse d’un pourcentage élevé de complications, telles que fractures, infections et pseudarthroses. Le but de notre étude est de rapporter la courbe de survie et les complications de ces allogreffes massives. 32 patients ont été évalués en terme de fractures, d’infections et de pseudarthroses, après mise en place d’allogreffes massives, le suivi moyen du groupe a été de 5 ans et 3 mois. le taux de fractures est de 13%, le taux d’infections de 16%. Nous avons trouvé un taux relativement bas de consolidation 25%. La survie de ces allogreffes, globalement est de 80,8% (± 18,7%) après 5 ans. le taux de survie de ces allogreffes à plus de 5 ans est de 80,8%, il est comparable aux autres études.

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Figures

Fig. 1
Fig. 1
Fixation of the allograft with the stem of the endoprosthesis, non-union 24 months postoperatively
Fig. 2
Fig. 2
Survival curve of the massive allograft reconstructions
Fig. 3
Fig. 3
Non-union and failure of fixation in an intercalary allograft reconstruction
See this image and copyright information in PMC

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