Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2009 Mar;144(5):782-8.
doi: 10.1111/j.1365-2141.2008.07512.x. Epub 2008 Dec 1.

Postdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events

Amanda M Brandow  1 , David C Brousseau, Julie A Panepinto
Affiliations
Comparative Study

Postdischarge pain, functional limitations and impact on caregivers of children with sickle cell disease treated for painful events

Amanda M Brandow et al. Br J Haematol. 2009 Mar.

Abstract

This study aimed to describe the outcomes of children with sickle cell disease (SCD) after discharge from medical care for vaso-occlusive painful events and to test the hypothesis that older age, longer length of hospital stay, and a history of frequent vaso-occlusive painful events will be associated with poor outcomes. Children aged 2-18 years with SCD treated in the emergency department or inpatient unit for a painful event were contacted after discharge to assess: days of pain, days of functional limitations for the child, and days of work/school absenteeism for the caregiver. Descriptive statistics were applied and multivariate logistic regression examined the association between the predictors and outcomes. Fifty-eight children were enrolled (mean age 10.8 +/- 4.8 years, 53.5% female). Postdischarge, 46.5% of children reported three or more days of pain, 54.3% had two or more days of functional limitations, and 24.3% of caregivers missed two or more days of work/school. Children with three or more prior painful events had increased odds of a poor outcome postdischarge (OR 1.79; 95% CI = 1.026, 3.096). In conclusion, acute vaso-occlusive painful events impact the lives of children with SCD and their caregivers, even after discharge to home.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: None for any of the authors

Figures

Figure 1
Figure 1
Proportion of children/caregivers experiencing primary outcomes.
See this image and copyright information in PMC

References

    1. Barbarin OA, Whitten CF, Bond S, Conner-Warren R. The Social and Cultural Context of Coping with Sickle Cell Disease: II. The Role of Financial Hardship in Adjustment to Sickle Cell Disease. Journal of Black Psychology. 1999;25:294–315.
    1. Brousseau DC, Scott JP, Hillery CA, Panepinto JA. The Effect of Magnesium on Length of Stay for Pediatric Sickle Cell Pain Crisis. Academic Emergency Medicine. 2004;11:968–972. - PubMed
    1. Charache S, Terrin ML, Moore RD, Dover GJ, Barton FB, Eckert SV, McMahon RP, Bonds DR. Effect of Hydroxyurea on the Frequency of Painful Crises in Sickle Cell Anemia. New England Journal of Medicine. 1995;332:1317–1322. - PubMed
    1. Dampier C, Setty Y, Eggleston b, Brodecki D, O’Neal P, Stuart M. Vaso-Occlusion in Children with Sickle Cell Disease: Clinical Characteristics and Biologic Correlates. Journal of Pediatric Hematology Oncology. 2004;26:785–790. - PubMed
    1. Dampier C, Ely E, Brodecki D, O’Neal P. Home Management of Pain in Sickle Cell Disease: A Daily Diary in Children and Adolescents. Journal of Pediatric Hematology Oncology. 2002a;24:643–647. - PubMed

Publication types

MeSH terms

Substances