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. 1991 Jul 15;47(7):721-4.
doi: 10.1007/BF01958826.

L-tyrosine induces tyrosinase expression via a posttranscriptional mechanism

A Slominski  1 , R Costantino
Affiliations

L-tyrosine induces tyrosinase expression via a posttranscriptional mechanism

A Slominski et al. Experientia. .

Abstract

Exposure of hamster amelanotic melanoma cells to L-tyrosine caused a time-dependent increase of tyrosinase protein concentrations, tyrosinase activity and level of cell pigmentation. In contrast, Northern blot analysis using mouse tyrosinase cDNA showed a steady level of tyrosinase mRNA. Thus in hamster melanoma cells the stimulation of intracellular tyrosinase concentration by L-tyrosine is mediated mainly via a posttranscriptional mechanism.

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References

    1. Pigment Cell Res. 1989 Mar-Apr;2(2):109-16 - PubMed
    1. Proc Natl Acad Sci U S A. 1988 Oct;85(19):7241-5 - PubMed
    1. Pharmacol Toxicol. 1989 Aug;65(2):100-3 - PubMed
    1. J Theor Biol. 1990 Mar 8;143(1):123-38 - PubMed
    1. J Biol Chem. 1990 Mar 25;265(9):4771-4 - PubMed

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