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Review
. 1991 Mar;111(3):170-81.
doi: 10.1248/yakushi1947.111.3_170.

[From nucleic acids to proteins]

[Article in Japanese]
Affiliations
Review

[From nucleic acids to proteins]

[Article in Japanese]
M Ikehara. Yakugaku Zasshi. 1991 Mar.

Abstract

Since elucidation of structure of deoxyribonucleic acid (DNA) as genetic material, it was established that DNA makes ribonucleic acid, which makes protein according to the original information given in DNA base as base sequences. From these basic idea of genetic flow system there was emerged the word "protein engineering". According to this principle, engineering of h-lysozyme, RNase H and their relevant proteins was described. A triosephosphate isomerase barrel type protein was designed and expressed.

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