Waste not, want not: a viral RNA degradation product modulates west nile virus pathogenesis
- PMID: 19064251
- DOI: 10.1016/j.chom.2008.11.004
Waste not, want not: a viral RNA degradation product modulates west nile virus pathogenesis
Abstract
In this issue of Cell Host & Microbe, Pijlman et al. define the structure and mechanism of generation of a small viral noncoding RNA present in flavivirus-infected cells that has a marked impact on the fate of infected cells and virulence in vivo.
Comment on
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A highly structured, nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity.Cell Host Microbe. 2008 Dec 11;4(6):579-91. doi: 10.1016/j.chom.2008.10.007. Cell Host Microbe. 2008. PMID: 19064258
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