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Comparative Study
. 2008 Sep-Oct;16(5):211-6.
doi: 10.1080/09273940802409969.

Distinct cytokine patterns in the aqueous humor of children, adolescents and adults with uveitis

Karen M Sijssens  1 , Ger T Rijkers, Aniki Rothova, Jan S Stilma, Joke H de Boer
Affiliations
Comparative Study

Distinct cytokine patterns in the aqueous humor of children, adolescents and adults with uveitis

Karen M Sijssens et al. Ocul Immunol Inflamm. 2008 Sep-Oct.

Abstract

Purpose: To determine the immune mediator profile in relation to age in the aqueous humor (AqH) of patients with uveitis.

Methods: AqH of children, adolescents, and adults with uveitis was analyzed for 16 immune mediators.

Results: No significant differences were found for IL-8, RANTES, and IP-10. The concentrations of the remaining 13 mediators were significant lower in adults compared with children and adolescents, except for IL-6, which was higher.

Conclusions: Various immune mediators are present in higher concentrations in AqH of children and adolescents with different uveitis entities compared with that of adults, except IL-6, which was higher in adults.

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