Counting motors by force
- PMID: 19070567
- DOI: 10.1016/j.cell.2008.11.021
Counting motors by force
Abstract
Properties of the microtubule motor protein kinesin-1 have been well characterized in vitro but not in the viscous environment of a cell. By measuring the force that kinesin-1 exerts on lipid droplets in fly embryos, Shubeita et al. (2008) determine the number of active motors per droplet and find unexpected differences between motor regulation in vivo and in vitro.
Comment on
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Consequences of motor copy number on the intracellular transport of kinesin-1-driven lipid droplets.Cell. 2008 Dec 12;135(6):1098-107. doi: 10.1016/j.cell.2008.10.021. Cell. 2008. PMID: 19070579 Free PMC article.
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