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Comment
. 2008 Dec 12;135(6):1006-8.
doi: 10.1016/j.cell.2008.11.034.

Divided within: heterogeneity within adult stem cell pools

Marc H G P Raaijmakers  1 , David T Scadden
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Divided within: heterogeneity within adult stem cell pools

Marc H G P Raaijmakers et al. Cell. .
Free article

Abstract

In this issue, Wilson et al. (2008) demonstrate that there are two functional subsets of hematopoietic stem cells that have distinctive kinetics of cell cycling. They present evidence that cells may transition between the two kinetic states, establishing one subpopulation that is ready to proliferate and another that is a deeply quiescent reserve.

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