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. 2009 Jan 15;11(2):381-4.
doi: 10.1021/ol802642g.

Palladium-catalyzed Suzuki-Miyaura coupling of pyridyl-2-boronic esters with aryl halides using highly active and air-stable phosphine chloride and oxide ligands

David X Yang  1 , Steven L Colletti, Kevin Wu, Maoying Song, George Y Li, Hong C Shen
Affiliations

Palladium-catalyzed Suzuki-Miyaura coupling of pyridyl-2-boronic esters with aryl halides using highly active and air-stable phosphine chloride and oxide ligands

David X Yang et al. Org Lett. .

Abstract

The palladium-catalyzed Suzuki-Miyaura coupling of pyridyl-2-boronic esters provided an efficient approach to useful biaryl building blocks containing a 2-pyridyl moiety. The convenient reaction protocol demonstrates its potentially wide applications in medicinal chemistry.

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