This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Comment

. 2009 Jan 6;180(1):16-7.

doi: 10.1503/cmaj.081713. Epub 2008 Dec 10.

Thiazolidinediones: do harms outweigh benefits?

Lorraine L Lipscombe¹

Affiliations

Affiliation

¹ Institute for Clinical Evaluative Sciences, Department of Medicine, University of Toronto, and Women's College Hospital, Toronto, Ont. Lorraine.Lipscombe@ices.on.ca

PMID: 19073650
PMCID: PMC2612067
DOI: 10.1503/cmaj.081713

Comment

Thiazolidinediones: do harms outweigh benefits?

Lorraine L Lipscombe. CMAJ. 2009.

. 2009 Jan 6;180(1):16-7.

doi: 10.1503/cmaj.081713. Epub 2008 Dec 10.

Author

Lorraine L Lipscombe¹

Affiliation

¹ Institute for Clinical Evaluative Sciences, Department of Medicine, University of Toronto, and Women's College Hospital, Toronto, Ont. Lorraine.Lipscombe@ices.on.ca

PMID: 19073650
PMCID: PMC2612067
DOI: 10.1503/cmaj.081713

No abstract available

PubMed Disclaimer

Comment in

Thiazolidinedione use and the risk of fractures.
Reblin T. Reblin T. CMAJ. 2009 Apr 14;180(8):841. doi: 10.1503/cmaj.1090005. CMAJ. 2009. PMID: 19364797 Free PMC article. No abstract available.

Comment on

Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis.
Loke YK, Singh S, Furberg CD. Loke YK, et al. CMAJ. 2009 Jan 6;180(1):32-9. doi: 10.1503/cmaj.080486. Epub 2008 Dec 10. CMAJ. 2009. PMID: 19073651 Free PMC article.

Similar articles

Thiazolidinedione use and the risk of fractures.
Reblin T. Reblin T. CMAJ. 2009 Apr 14;180(8):841. doi: 10.1503/cmaj.1090005. CMAJ. 2009. PMID: 19364797 Free PMC article. No abstract available.
Thiazolidinedione use and the risk of fractures.
Toulis KA, Goulis DG, Anastasilakis AD. Toulis KA, et al. CMAJ. 2009 Apr 14;180(8):841-2; author reply 842-3. doi: 10.1503/cmaj.1090003. CMAJ. 2009. PMID: 19364796 Free PMC article. No abstract available.
Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis.
Loke YK, Singh S, Furberg CD. Loke YK, et al. CMAJ. 2009 Jan 6;180(1):32-9. doi: 10.1503/cmaj.080486. Epub 2008 Dec 10. CMAJ. 2009. PMID: 19073651 Free PMC article.
[Determining the current position regarding the value of pioglitazone for the therapy of diabetes].
Eckert S, Erdmann E, Lundershausen R, Forst T, Scherbaum WA, Schnell O, Standl E, Schumm-Draeger PM, Tschöpe D, Walter H, Weber M. Eckert S, et al. Dtsch Med Wochenschr. 2007 Dec;132(49):2650-3. doi: 10.1055/s-2007-993115. Dtsch Med Wochenschr. 2007. PMID: 18050033 German. No abstract available.
The safety of rosiglitazone in the treatment of type 2 diabetes.
Singh S, Loke YK. Singh S, et al. Expert Opin Drug Saf. 2008 Sep;7(5):579-85. doi: 10.1517/14740338.7.5.579. Expert Opin Drug Saf. 2008. PMID: 18759710 Review.

See all similar articles

Cited by

Advancement of artificial intelligence based treatment strategy in type 2 diabetes: A critical update.
Sen A, Mohanraj PS, Laxmi V, Ashique S, Vasudevan R, Aldahish A, Velu A, Das A, Ehsan I, Islam A, Yasmin S, Ansari MY. Sen A, et al. J Pharm Anal. 2025 Jun;15(6):101305. doi: 10.1016/j.jpha.2025.101305. Epub 2025 Apr 10. J Pharm Anal. 2025. PMID: 40678477 Free PMC article. Review.
Thiazolidinedione use and the risk of fractures.
Reblin T. Reblin T. CMAJ. 2009 Apr 14;180(8):841. doi: 10.1503/cmaj.1090005. CMAJ. 2009. PMID: 19364797 Free PMC article. No abstract available.
Adiponectin: an indispensable molecule in rosiglitazone cardioprotection following myocardial infarction.
Tao L, Wang Y, Gao E, Zhang H, Yuan Y, Lau WB, Chan L, Koch WJ, Ma XL. Tao L, et al. Circ Res. 2010 Feb 5;106(2):409-17. doi: 10.1161/CIRCRESAHA.109.211797. Epub 2009 Nov 25. Circ Res. 2010. PMID: 19940263 Free PMC article.
Double-blind, placebo-controlled clinical evaluation of an Ayurvedic formulation (GlucoCare capsules) in non-insulin dependent diabetes mellitus.
Sharma RK, Patki PS. Sharma RK, et al. J Ayurveda Integr Med. 2010 Jan;1(1):45-51. doi: 10.4103/0975-9476.59827. J Ayurveda Integr Med. 2010. PMID: 21829301 Free PMC article.
Alogliptin: a review of its use in the management of type 2 diabetes mellitus.
Scott LJ. Scott LJ. Drugs. 2010 Oct 22;70(15):2051-72. doi: 10.2165/11205080-000000000-00000. Drugs. 2010. PMID: 20883057 Review.

See all "Cited by" articles

References

1. Loke YK, Singh S, Furberg C. Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis. CMAJ 2009;180(1):32-9. - PMC - PubMed
1. Yki-Jarvinen H. Thiazolidinediones. N Engl J Med 2004;351:1106-18. - PubMed
1. Lago RM, Singh PP, Nesto RW. Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials. Lancet 2007;370:1129-36. - PubMed
1. Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007;356:2457-71. - PubMed
1. Singh S, Loke YK, Furberg CD. Long-term risk of cardiovascular events with rosiglitazone: a meta-analysis. JAMA 2007;298:1189-95. - PubMed

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Medical
- MedlinePlus Health Information