Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body

Editorial

Frank L Powell. Am J Physiol Lung Cell Mol Physiol. 2009 Feb.

. 2009 Feb;296(2):L156-7.

doi: 10.1152/ajplung.90597.2008. Epub 2008 Dec 12.

No abstract available

Comment on

Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body.
Liu X, He L, Stensaas L, Dinger B, Fidone S. Liu X, et al. Am J Physiol Lung Cell Mol Physiol. 2009 Feb;296(2):L158-66. doi: 10.1152/ajplung.90383.2008. Epub 2008 Oct 31. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 18978039 Free PMC article.

Aβ degradation or cerebral perfusion? Divergent effects of multifunctional enzymes.
Miners JS, Palmer JC, Tayler H, Palmer LE, Ashby E, Kehoe PG, Love S. Miners JS, et al. Front Aging Neurosci. 2014 Sep 11;6:238. doi: 10.3389/fnagi.2014.00238. eCollection 2014. Front Aging Neurosci. 2014. PMID: 25309424 Free PMC article. Review.
Changes in carotid body and nTS neuronal excitability following neonatal sustained and chronic intermittent hypoxia exposure.
Mayer CA, Wilson CG, MacFarlane PM. Mayer CA, et al. Respir Physiol Neurobiol. 2015 Jan 1;205:28-36. doi: 10.1016/j.resp.2014.09.015. Epub 2014 Sep 26. Respir Physiol Neurobiol. 2015. PMID: 25266393 Free PMC article.
A possible important regulatory role of estrogen in obstructive sleep apnea hypoventilation syndrome.
Zhou P, Li H, Li H, Chen Y, Lv Y. Zhou P, et al. Front Med (Lausanne). 2025 Mar 3;12:1369393. doi: 10.3389/fmed.2025.1369393. eCollection 2025. Front Med (Lausanne). 2025. PMID: 40098932 Free PMC article. Review.
Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease.
Iturriaga R, Del Rio R, Idiaquez J, Somers VK. Iturriaga R, et al. Biol Res. 2016 Feb 26;49:13. doi: 10.1186/s40659-016-0073-8. Biol Res. 2016. PMID: 26920146 Free PMC article. Review.

1. Canning BJ Neurokinin3 receptor regulation of the airways. Vascul Pharmacol 45: 227–234, 2006. - PubMed
1. Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell 112: 645–657. - PMC - PubMed
1. Lam SY, Tipoe GL, Liong EC, Fung ML. Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body. Histochem Cell Biol 130: 549–559, 2008. - PubMed
1. Liu X, He L, Stensaas L, Dinger B, Fidone S. Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body. Am J Physiol Lung Cell Mol Physiol (October 31, 2008). doi:10.1152/ajplung.90383.2008. - DOI - PMC - PubMed
1. Mazzone SB, Canning BJ. Central nervous system control of the airways: pharmacological implications. Curr Opin Pharmacol 2: 200–208, 2002. - PubMed