Methadone exposure during lactation
- PMID: 19074706
- PMCID: PMC2602642
Methadone exposure during lactation
Abstract
Question: One of my patients is currently using methadone for maintenance of opioid dependence. She wants to breastfeed. Is breastfeeding safe for her infant?
Answer: The exposure of infants to methadone through their mothers' breast milk is minimal. Women using methadone for treatment of opioid dependence should not be discouraged from breastfeeding. The benefits of breastfeeding largely outweigh any theoretical minimal risks.
QUESTION: Une de mes patientes prend présentement de la méthadone pour la prise en charge de la dépendance aux opiacés. Elle souhaite allaiter son bébé. Est-ce sans danger pour le nourrisson?
RÉPONSE: L’exposition des nourrissons à la méthadone dans le lait maternel est minime. Il ne faudrait pas décourager l’allaitement par les femmes qui prennent de la méthadone pour le traitement d’une dépendance aux opiacés. Les avantages de l’allaitement compensent largement les risques théoriques minimes.
Similar articles
-
Breastfeeding considerations of opioid dependent mothers and infants.MCN Am J Matern Child Nurs. 2012 Jul-Aug;37(4):236-40. doi: 10.1097/NMC.0b013e318251056c. MCN Am J Matern Child Nurs. 2012. PMID: 22739479
-
[Breast feeding during methadon- and buprenorphin therapy].Klin Padiatr. 2011 Dec;223(7):408-13. doi: 10.1055/s-0031-1283193. Epub 2011 Sep 26. Klin Padiatr. 2011. PMID: 21969026 Review. German.
-
Estimated infant exposure to enantiomer-specific methadone levels in breastmilk.Breastfeed Med. 2011 Dec;6(6):377-84. doi: 10.1089/bfm.2010.0060. Epub 2011 Feb 24. Breastfeed Med. 2011. PMID: 21348770 Free PMC article.
-
Pharmacologic treatment of hyperthyroidism during lactation.Can Fam Physician. 2009 Aug;55(8):797-8. Can Fam Physician. 2009. PMID: 19675263 Free PMC article.
-
Peripartum Anesthetic Management of the Opioid-tolerant or Buprenorphine/Suboxone-dependent Patient.Clin Obstet Gynecol. 2017 Jun;60(2):447-458. doi: 10.1097/GRF.0000000000000288. Clin Obstet Gynecol. 2017. PMID: 28426507 Review.
Cited by
-
Pain relief after cesarean section: Oral methadone vs. intramuscular pethidine.J Res Med Sci. 2012 Feb;17(2):143-7. J Res Med Sci. 2012. PMID: 23264787 Free PMC article.
-
Maternal Substance Use and Neonatal Abstinence Syndrome: A Descriptive Study.Matern Child Health J. 2015 Aug;19(8):1756-65. doi: 10.1007/s10995-015-1689-y. Matern Child Health J. 2015. PMID: 25656717
References
-
- Dawe S, Harnett P. Reducing potential for child abuse among methadone-maintained parents: results from a randomized controlled trial. J Subst Abuse Treat. 2007;32(4):381–90. Epub 2006 Dec 8. - PubMed
-
- Daley M, Argeriou M, McCarty D, Callahan JJ, Jr, Shepard DS, Williams CN. The costs of crime and the benefits of substance abuse treatment for pregnant women. J Subst Abuse Treat. 2000;19(4):445–58. - PubMed
-
- Kintz P, Villain M, Dumestre-Toulet V, Capolaghi B, Cirimele V. Methadone as a chemical weapon: two fatal cases involving babies. Ther Drug Monit. 2005;27(6):741–3. - PubMed
-
- Loimer N, Schmid R. The use of plasma level to optimize maintenance treatment. Drug Alcohol Depend. 1992;30(3):241–6. - PubMed
-
- Robinson AE, Williams FM. The distribution of methadone in man. J Pharm Pharmacol. 1971;23(5):353–8. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical