Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Dec;7(2):62-5.
doi: 10.1097/01.cnd.0000188865.88167.62.

Parotid gland injections of botulinum toxin a are effective in treating sialorrhea in amyotrophic lateral sclerosis

Kevin R Scott  1 , Milind J Kothari, Y Swami Venkatesh, Tamara Murphy, Zachary Simmons
Affiliations

Parotid gland injections of botulinum toxin a are effective in treating sialorrhea in amyotrophic lateral sclerosis

Kevin R Scott et al. J Clin Neuromuscul Dis. 2005 Dec.

Abstract

Objective: : The objective of this study was to determine the safety and efficacy of botulinum toxin A in ameliorating refractory sialorrhea and improving quality of life in patients with amyotrophic lateral sclerosis.

Materials and methods: : Six patients with bulbar ALS received bilateral parotid gland injections of botulinum toxin A.

Results: : No adverse effects occurred. Tissue use decreased in 5 of 7 patients at a dose of 10 units and in 3 of 4 patients at a dose of 20 units. Self-reported quality of life did not change in most.

Conclusions: : Parotid gland injections of botulinum toxin appear safe and may be helpful in some patients with ALS for the treatment of sialorrhea.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

LinkOut - more resources