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Comment
. 2008 Jan;1(1):8-10.
doi: 10.1038/mi.2007.8.

Location, location, location: B-cell differentiation in the gut lamina propria

A Cerutti  1
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Free article
Comment

Location, location, location: B-cell differentiation in the gut lamina propria

A Cerutti. Mucosal Immunol. 2008 Jan.
Free article

Abstract

The intestinal immune system includes an immunoglobulin (Ig)A-inductive site represented by Peyer's patches (PPs) and an IgA effector site represented by the lamina propria (LP). This canonical map of intestinal IgA production has been blurred recently by studies showing the presence of active IgA class switching in the LP. Here we discuss the functional implications and controversial nature of these findings.

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