Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jan;16(1):91-3.
doi: 10.1038/nsmb.1539. Epub 2008 Dec 14.

An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II

Linfeng Huang  1 , Alexandra M E Jones, Iain Searle, Kanu Patel, Hannes Vogler, Nina C Hubner, David C Baulcombe
Affiliations

An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II

Linfeng Huang et al. Nat Struct Mol Biol. 2009 Jan.

Abstract

Genetic evidence indicates that plant-specific homologs of DNA-dependent RNA polymerase (Pol) II large subunits form Pol IV and Pol V complexes involved in small interfering RNA production and RNA-directed DNA methylation. Here we describe evidence that Pol V contains subunits shared with Pol II, but that RNA polymerase II subunit (RPB)-4 is missing from Pol V and that RPB5 is present as a Pol V-specific isomer, RPB5b. Pol V also has other proteins that are not present in Pol II, consistent with a role of this complex as an effector of silencing.

PubMed Disclaimer

References

    1. Genes Dev. 2005 Oct 1;19(19):2301-6 - PubMed
    1. Trends Biochem Sci. 1996 Nov;21(11):425-6 - PubMed
    1. Nat Genet. 2005 Jul;37(7):761-5 - PubMed
    1. Science. 2005 Jul 15;309(5733):467-9 - PubMed
    1. J Biol Chem. 1998 Mar 6;273(10):5631-7 - PubMed

Publication types

MeSH terms

LinkOut - more resources