doi: 10.1080/21548331.1991.11705279.
The actions of NSAIDs
Affiliations
- PMID: 1907978
- DOI: 10.1080/21548331.1991.11705279
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The actions of NSAIDs
Hosp Pract (Off Ed).
.
Abstract
The ability of aspirin and related drugs to inhibit prostaglandin biosynthesis accounts for many effects of NSAIDs but does not completely explain their efficacy against inflammation. An additional mechanism may be disruption of the intracellular signal pathways responsible for activation of inflammatory cells--notably, neutrophils.
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