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Comment
. 2008 Dec;15(6):795-6.
doi: 10.1016/j.devcel.2008.11.013.

ER stress and lipogenesis: a slippery slope toward hepatic steatosis

Sana Basseri  1 , Richard C Austin
Affiliations
Free article
Comment

ER stress and lipogenesis: a slippery slope toward hepatic steatosis

Sana Basseri et al. Dev Cell. 2008 Dec.
Free article

Abstract

Endoplasmic reticulum (ER) stress and activation of the unfolded protein response have been linked to many human disorders, including obesity, type 2 diabetes, and cancer. In this issue of Developmental Cell,Rutkowski et al. (2008) show that unresolved ER stress contributes to metabolic dysfunction and hepatic steatosis.

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