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. 2008 Sep-Oct;74(5):685-690.
doi: 10.1016/S1808-8694(15)31377-X.

Experimental study on the influence of facial muscle activity on the facial mesostructure bones in rabbits

Andre Ricardo Mateus  1 , José Eduardo Lutaif Dolci  2 , Henrique Olavo de Olival Costa  3 , Flávia Coelho Sousa  4 , Noemi di Biase  5
Affiliations

Experimental study on the influence of facial muscle activity on the facial mesostructure bones in rabbits

Andre Ricardo Mateus et al. Braz J Otorhinolaryngol. 2008 Sep-Oct.

Abstract

Based on the functional matrix concept, scientists developed the hypothesis that soft tissue acting on certain bone pieces determines the process of facial growth. The possibility to modify muscle influence in the phase of facial development, or in postoperative of corrective surgery is of great preventive importance and it should be better investigated, since it could reduce the number and impact of these procedures.

Study design: experimental in rabbits.

Aim: to estimate the relevance of facial muscle activity on facial bones in lab rabbits.

Materials and methods: 37 rabbits of two months of age were studied, divided in a study group and a control group, were followed up for a period of 4 months. The study group animals had their facial nerves cut at the cervical root in one side. The facial mesostructure of the animals was removed in block for later morphometric studies through computer graphics made out of the digital pictures of the specimens. Results were submitted for comparative statistical analysis.

Conclusion: The lack of muscle activity in half of the face produces an ipsilateral shift of the facial mesostructure in developing rabbits.

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Figures

Figure 1
Figure 1
Comparative schematic representation of facial mesostructure muscles in humans and in rabbits (Mateus, 2007)
Figure 2
Figure 2
Arrows show the force vectors produced by muscles operating on both halfs of the face. (A) symmetrically, and (B) asymmetrically (Mateus, 2007)
Figure 3
Figure 3
The chart shows lateral deviations of the facial mesostructure in both study groups
Figure 4
Figure 4
The chart shows the number of rabbits that demonstrated each degree of lateral deviation of the facial mesostructure, in both study groups
See this image and copyright information in PMC

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