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. 2009 Mar 15;278(1-2):64-5.
doi: 10.1016/j.jns.2008.11.014. Epub 2008 Dec 13.

Topiramate weight loss in migraine patients

Antonella Alberici  1 , Barbara Borroni, Filippo Manelli, Simona Griffini, Paola Zavarise, Alessandro Padovani, Giorgio Dalla Volta
Affiliations

Topiramate weight loss in migraine patients

Antonella Alberici et al. J Neurol Sci. .

Abstract

Topiramate (TPM) is generally recognized efficacious and safe in migraine prevention. A significant proportion of patients undergoing TPM administration may show weight loss. In epileptic subjects, high body mass index (BMI) was found to be predictive of weight loss under TPM therapy. We therefore aimed to study whether common clinical determinants may be associated to TPM weigh loss in migraine patients. In our clinical series, high BMI was not found a predictor of weight loss under TPM treatment. Unknown genetic and environmental factors that may determine the courses of weight loss under TPM therapy are still do be identified.

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