UK guidelines for the medical and laboratory screening of sperm, egg and embryo donors (2008)

Abstract

This article updates the 1999 British Andrology Society (BAS) guidelines for the screening of sperm donors and the 2000 British Fertility Society (BFS) guidelines for the screening of egg and embryo donors and combines the new recommendations into a single document. This was achieved by a multidisciplinary working group composed of representatives from the Association of Biomedical Andrologists, the Association of Clinical Embryologists, the BAS, the BFS and the Royal College of Obstetricians and Gynecologists. The major changes to the guidelines include a requirement to consider a donor's risk of transmissible spongiform encephalopathies and the recommendation to screen for human T cell lymphotropic viruses 1 and 2. The role of nucleic amplification tests for the detection of blood borne viruses such as HIV is discussed, but it remains the recommendation that this be achieved by serological testing to detect antibody or antigen as appropriate with a quarantine period of 180 days.