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. 1991 Sep;59(9):3337-9.
doi: 10.1128/iai.59.9.3337-3339.1991.

Functional evidence that the Ser-195 residue of staphylococcal exfoliative toxin A is essential for biological activity

G Prévost  1 , S Rifai, M L Chaix, Y Piémont
Affiliations

Functional evidence that the Ser-195 residue of staphylococcal exfoliative toxin A is essential for biological activity

G Prévost et al. Infect Immun. 1991 Sep.

Abstract

The substitution of the serine 195 residue of staphylococcal exfoliative toxin A by a cysteine residue led to a biologically inactive protein. This result is consistent with the hypothesis that exfoliative toxin A could be a protease or a lipase. However, no protease or lipase activity was detected with the native toxin.

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