Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Jul-Aug;16(4):238-46.
doi: 10.1590/s1678-77572008000400003.

Slow-release fluoride devices: a literature review

Affiliations
Review

Slow-release fluoride devices: a literature review

Juliano Pelim Pessan et al. J Appl Oral Sci. 2008 Jul-Aug.

Abstract

Although the prevalence of caries has decreased dramatically over the past decades, it has become a polarised disease, with most of subjects presenting low caries levels and few individuals accounting for most of the caries affected surfaces. Thus it become evident for the need of clinical approaches directed at these high-risk patients, in order to overcome problems related to compliance and low attendance at dental care centres. Slow-release fluoride devices were developed based on the inverse relationship existing between intra-oral fluoride levels and dental caries experience. The two main types of slow-release devices - copolymer membrane type and glass bead - are addressed in the present review. A substantial number of studies have demonstrated that these devices are effective in raising intra-oral F concentrations at levels able to reduce enamel solubility, resulting in a caries-protective effect. Studies in animals and humans demonstrated that the use of these devices was able to also protect the occlusal surfaces, not normally protected by conventional fluoride regimens. However, retention rates have been shown to be the main problem related to these devices and still requires further improvements. Although the results of these studies are very promising, further randomised clinical trials are needed in order to validate the use of these devices in clinical practice. The concept of continuously providing low levels of intra-oral fluoride has great potential for caries prevention in high caries-risk groups.

PubMed Disclaimer

Figures

FIGURE 1
FIGURE 1. Schematic cross-sectional view of the copolymer device, which originally had 8 mm in length, 3 mm in width, and 2 mm in tickness. Modified from Mirth, et al. (1982)
FIGURE 2
FIGURE 2. Original glass device attached to the buccal surface of the first upper right permanent molar
FIGURE 3
FIGURE 3. Kidney-shaped device bonded to the upper first permanent molar tooth
FIGURE 4
FIGURE 4. The latest version of the fluoride glass slow-release device and plastic retention bracket
FIGURE 5
FIGURE 5. Latest glass device and bracket attached to upper first permanent molar tooth

References

    1. Adair SM, Whitford GM, Hanes CM. In vitro effect of human saliva on the output of fluoride from controlled release devices. Pediatr Dent. 1994;16(6):410–412. - PubMed
    1. Adair SM, Whitford GM, McKnight-Hanes C. Effect of artificial saliva and calcium on fluoride output of controlled-release devices. Caries Res. 1994;28(1):28–34. - PubMed
    1. Adderly D, Shern R, Emilson C. Evaluation of an intra-oral device for the controlled release of fluoride in primates. J Dent Res. 1981;60(sp issue):573–573. [abstract 1064]
    1. Alaçam A, Ulusu T, Bodur H, Oztas N, Oren MC. Salivary and urinary fluoride levels after 1-month use of fluoride-releasing removable appliances. Caries Res. 1996;30(3):200–203. - PubMed
    1. Al-Ibrahim NS. I. Unilateral versus bilateral placement of slowrelease fluoride glass device. II. In vitro assessment of slow-release fluoride glass device. Leeds(UK): University of Leeds; 2007. [thesis]