Acute kidney injury in burns: a story of volume and inflammation
- PMID: 19090961
- PMCID: PMC2646343
- DOI: 10.1186/cc7106
Acute kidney injury in burns: a story of volume and inflammation
Abstract
Acute kidney injury occurs in approximately one-quarter to one-third of patients with major burn injury. Apart from the usual suspects - such as older age, severity of burn injury, sepsis and multiple organ dysfunction - volume overload probably has an important role in the pathogenesis of acute kidney injury.
Comment on
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Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study.Crit Care. 2008;12(5):R124. doi: 10.1186/cc7032. Epub 2008 Oct 10. Crit Care. 2008. PMID: 18847465 Free PMC article.
References
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- Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P, the ADQI workgroup Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8:R204–R212. doi: 10.1186/cc2872. - DOI - PMC - PubMed
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