Two receptor binding regions of human FSH show sense-antisense similarity to the human FSH receptor
- PMID: 1909119
- DOI: 10.1016/0006-291x(91)91364-i
Two receptor binding regions of human FSH show sense-antisense similarity to the human FSH receptor
Abstract
The sequences of two receptor binding regions of the beta-subunit of the human follicle-stimulating hormone (hFSH-beta) were compared with the DNA-derived antisense peptide sequence of the hFSH receptor. A striking sense-antisense similarity was established between these receptor binding regions and the hFSH receptor. Based on this sense-antisense similarity four putative hormone binding regions on the N-terminal extracellular region of the hFSH receptor are identified.
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