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Comparative Study
. 1991 Aug 30;179(1):266-71.
doi: 10.1016/0006-291x(91)91364-i.

Two receptor binding regions of human FSH show sense-antisense similarity to the human FSH receptor

J W Slootstra  1 , E W Roubos
Affiliations
Comparative Study

Two receptor binding regions of human FSH show sense-antisense similarity to the human FSH receptor

J W Slootstra et al. Biochem Biophys Res Commun. .

Abstract

The sequences of two receptor binding regions of the beta-subunit of the human follicle-stimulating hormone (hFSH-beta) were compared with the DNA-derived antisense peptide sequence of the hFSH receptor. A striking sense-antisense similarity was established between these receptor binding regions and the hFSH receptor. Based on this sense-antisense similarity four putative hormone binding regions on the N-terminal extracellular region of the hFSH receptor are identified.

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