Review
doi: 10.7326/0003-4819-86-3-323.
Epstein-Barr virus and human malignancy
- PMID: 190930
- DOI: 10.7326/0003-4819-86-3-323
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Review
Epstein-Barr virus and human malignancy
Ann Intern Med.
1977 Mar.
Abstract
The association of the Epstein-Barr virus and two human malignancies, Burkitt's lumphoma and nasopharyngeal carcinoma, is reviewed. Seroepidemiologic, virologic, and immunologic evidence is summarized, and several hypotheses regarding a possible etiologic role for the Epstein-Barr virus in these tumors are presented. With our current state of knowledge we cannot conclude that the Ipstein-Barr virus is oncogenic in man, nor can we yet ascertain the biological and clinical significance of its association with Burkitt's lymphoma and nasopharyngeal carcinoma.
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