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Review
. 2008 Dec;51(12):1056-65.
doi: 10.1007/s11427-008-0148-z. Epub 2008 Dec 18.

PII, the key regulator of nitrogen metabolism in the cyanobacteria

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Review

PII, the key regulator of nitrogen metabolism in the cyanobacteria

Ying Zhang et al. Sci China C Life Sci. 2008 Dec.

Abstract

PII proteins are a protein family important to signal transduction in bacteria and plants. PII plays a critical role in regulation of carbon and nitrogen metabolism in cyanobacteria. Through conformation change and covalent modification, which are regulated by 2-oxoglutarate, PII interacts with different target proteins in response to changes of cellular energy status and carbon and nitrogen sources in cyanobacteria and regulates cellular metabolism. This article reports recent progress in PII research in cyanobacteria and discusses the mechanism of PII regulation of cellular metabolism.

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