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Case Reports
. 2009 Jul;34(5):e167-9.
doi: 10.1111/j.1365-2230.2008.03041.x. Epub 2008 Dec 15.

Lupus vulgaris at the site of BCG vaccination: report of three cases

K Farsinejad  1 , M Daneshpazhooh, H Sairafi, M Barzegar, M Mortazavizadeh
Affiliations
Case Reports

Lupus vulgaris at the site of BCG vaccination: report of three cases

K Farsinejad et al. Clin Exp Dermatol. 2009 Jul.

Abstract

Lupus vulgaris (LV) is a rare complication of the bacille Calmette-Guérin (BCG) vaccination, and about 65 cases of inoculation tuberculosis resembling LV have been reported in the literature. We report three cases of LV, developing many years later at the inoculation site of BCG vaccine. All three cases had a single BCG vaccination, with a LV lesion at or in the vicinity of the vaccination site, a strong positive Mantoux test, noncaseating granuloma histologically, and two of the patients had a positive PCR result for mycobacterial complex. One of the patients had an unusually delayed appearance of the LV lesion, after an interval of about 17 years, and another case was remarkable because of the large size of the lesion (210 x 110 mm).

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