Breast cancer and melanoma in the same pedigree
- PMID: 19094839
Breast cancer and melanoma in the same pedigree
Abstract
This report is to document the occurrence of breast cancer and melanoma within either the same pedigree or the same patient and to make others aware of this association. A series of 52 patient pedigrees is presented from one clinical practice in which both breast cancer and melanoma were found over a 30-month period. It is suggested that formal pedigrees be obtained in addition to routine medical history questionnaires when either breast cancer or melanoma are encountered. It is further suggested that patients with either malignancy be screened for the other.
Similar articles
-
Inherited predisposition to cancer: a historical overview.Am J Med Genet C Semin Med Genet. 2004 Aug 15;129C(1):5-22. doi: 10.1002/ajmg.c.30026. Am J Med Genet C Semin Med Genet. 2004. PMID: 15264268
-
Germline mutations in CDKN2A are infrequent in female patients with melanoma and breast cancer.Melanoma Res. 2009 Aug;19(4):211-4. doi: 10.1097/CMR.0b013e3283281057. Melanoma Res. 2009. PMID: 19571771
-
Cancer risk assessment and the genetic counseling process: using hereditary breast and ovarian cancer as an example.Med Princ Pract. 2008;17(3):173-89. doi: 10.1159/000117790. Epub 2008 Apr 10. Med Princ Pract. 2008. PMID: 18408385 Review.
-
Genetic predisposition to ocular melanoma.Eye (Lond). 1999;13 ( Pt 1):43-6. doi: 10.1038/eye.1999.9. Eye (Lond). 1999. PMID: 10396383 Review.
-
Confirmed cancer trends in families of patients with multiple cancers including cutaneous melanoma.Br J Dermatol. 2008 Feb;158(2):429-31. doi: 10.1111/j.1365-2133.2007.08328.x. Epub 2007 Nov 28. Br J Dermatol. 2008. PMID: 18047508 No abstract available.
Cited by
-
CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1.J Invest Dermatol. 2013 May;133(5):1294-301. doi: 10.1038/jid.2012.487. Epub 2013 Jan 10. J Invest Dermatol. 2013. PMID: 23303449 Free PMC article.
MeSH terms
LinkOut - more resources
Medical