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Editorial
. 2009 Feb;55(2):206-8.
doi: 10.1373/clinchem.2008.119206. Epub 2008 Dec 18.

Inhibition of endothelial nitric oxide synthase by C-reactive protein: clinical relevance

Ishwarlal Jialal, Subodh Verma, Sridevi Devaraj
Editorial

Inhibition of endothelial nitric oxide synthase by C-reactive protein: clinical relevance

Ishwarlal Jialal et al. Clin Chem. 2009 Feb.
No abstract available

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Conflict of interest statement

Authors’ Disclosures of Potential Conflicts of Interest: No authors declared any potential conflicts of interest.

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References

    1. Verma S, Wang CH, Li SH, Dumont AS, Fedak PW, Badiwala MV, et al. A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation. 2002;106:913–9. - PubMed
    1. Venugopal SK, Devaraj S, Yuhanna I, Shaul P, Jialal I. Demonstration that C-Reactive protein decrease eNOS expression and bioactivity in human aortic endothelial cells. Circulation. 2002;106:1439–41. - PubMed
    1. Dasu MR, Devaraj S, Du Clos TW, Jialal I. The biological effects of CRP are not attributable to endotoxin contamination: evidence from TLR4 knockdown human aortic endothelial cells. J Lipid Res. 2007;48:509–12. - PubMed
    1. Singh U, Devaraj S, Vasquez-Vivar J, Jialal I. CRP decreases endothelial nitric oxide synthase via uncoupling. J Mol Cell Cardiol. 2007;43:780–91. - PMC - PubMed
    1. Mineo C, Gormley AK, Yuhanna IS, Osborne-Lawrence S, Gibson LL, Hahner L, et al. FcγRIIB mediates C-reactive protein inhibition of endothelial NO synthase. Circ Res. 2005;97:1124–31. - PubMed

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