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Multicenter Study
. 2008 Sep;126(5):252-6.
doi: 10.1590/s1516-31802008000500002.

Predictors of quality of life among patients on dialysis in southern Brazil

Maristela Bohlke  1 , Diego Leite Nunes, Stela Scaglioni Marini, Cleison Kitamura, Marcia Andrade, Maria Paula Ost Von-Gysel
Affiliations
Multicenter Study

Predictors of quality of life among patients on dialysis in southern Brazil

Maristela Bohlke et al. Sao Paulo Med J. 2008 Sep.

Abstract
in English, Portuguese

Context and objective: Quality of life (QoL) is considered important as an outcome measurement, especially for long-term diseases such as chronic renal failure. The present study searched for predictors of QoL in a sample of patients undergoing dialysis in southern Brazil.

Design and setting: This was a cross-sectional study developed in three southern Brazilian dialysis facilities.

Methods: Health-related QoL of patients on hemodialysis or peritoneal dialysis was measured using the generic Short Form-36 (SF-36) health survey questionnaire. The results were correlated with sociodemographic, clinical and laboratory variables. The analysis was adjusted through multiple linear regression.

Results: A total of 140 patients were assessed: 94 on hemodialysis and 46 on peritoneal dialysis. The mean age was 54.2 +/- 15.4 years, 48% were men and 76% were white. The predictors of higher (better) physical component summary in SF-36 were: younger age (beta-0.16; 95% confidence interval, CI: -0.27 to -0.05), shorter time on dialysis (beta-0.06; 95% CI: -0.09 to -0.02) and lower Khan comorbidity-age index (beta 5.16; 95% CI: 1.7-8.6). The predictors of higher mental component summary were: being employed (beta 8.4; 95% CI: 1.7-15.1), being married or having a marriage-like relationship (beta 4.56; 95% CI: 0.9-8.2), being on peritoneal dialysis (beta 4.9; 95% CI: 0.9-8.8) and not having high blood pressure (beta 3.9; 95% CI: 0.3-7.6).

Conclusions: Age, comorbidity and length of time on dialysis were the main predictors of physical QoL, whereas socioeconomic issues especially determined mental QoL.

CONTEXTO E OBJETIVO:: A qualidade de vida (QoL) é considerada uma importante medida de desfecho, especialmente no manejo de doenças de longa evolução, como a doença renal crônica. O presente estudo avaliou os preditores de QoL em uma amostra de pacientes tratados por diálise.

TIPO DE ESTUDO E LOCAL:: Estudo transversal com coleta de dados em três centros de diálise do sul do Brasil.

MÉTODOS:: Avaliação de pacientes tratados por diálise, com aplicação do questionário genérico SF-36 (Short Form-36) e correlação com variáveis demográficas, socioeconômicas, clínicas e laboratoriais. A análise foi ajustada por regressão linear múltipla.

Resultados:: Foram avaliados 140 pacientes, 94 tratados por hemodiálise e 46 por diálise peritoneal, com idade 54.2 ± 15,4 anos, 48% homens e 76% brancos. A dimensão física do SF-36 esteve associada à idade (β -0,17 intervalo de confiança, IC 95% -0,27-0,58), ao tempo em diálise (β -0,05 IC 95% -0,08-0,01) e ao índice de idade-comorbidade de Khan mais elevado (β 5,52 IC 95% 2,1-8,9). A dimensão mental esteve associada a ocupação remunerada (β 8,4 IC 95% 1,7-15,1), união estável (β 4,56 IC 95% 0,9-8,2), tratamento por diálise peritoneal (β 4,9 IC 95% 0,9-8,8) e ao fato de não ser hipertenso (β 3,9 IC 95% 0,3-7,6).

CONCLUSÕES:: Os pacientes mais jovens, tratados por diálise há menos tempo e com um menor número de comorbidades apresentaram melhor QoL do ponto de vista físico. A QoL mental foi melhor em pacientes que desempenham atividade remunerada, são casados, tratados por diálise peritoneal e não-hipertensos.

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Conflict of interest statement

Conflict of interest: None

References

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