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. 2009 Mar;39(3):232-8.
doi: 10.1007/s00247-008-1079-3. Epub 2008 Dec 20.

Brain ultrasonography findings in neonates with exposure to cocaine during pregnancy

Marian van Huis  1 , Anne A M W van Kempen, Myrthe Peelen, Maaike Timmers, Kees Boer, Bert J Smit, Rick R Van Rijn
Affiliations

Brain ultrasonography findings in neonates with exposure to cocaine during pregnancy

Marian van Huis et al. Pediatr Radiol. 2009 Mar.

Abstract

Background: Cocaine exposure during pregnancy has been reported to have detrimental effects on the fetus.

Objective: To describe the findings on cranial ultrasonography (CUS) as part of a neonatal screening programme for exposed neonates.

Materials and methods: The study was a semiprospective analysis of a 12-year cohort of neonates born to mothers who had used cocaine during their pregnancy and who had follow-up according to a strict clinical protocol.

Results: In total, 154 neonates (78 boys, 76 girls) were included, of whom 29 (19%) were born preterm, and 125 (81%) were born full-term. Abnormalities on CUS were seen in 37 neonates (24%; 95% CI 18-31%). The abnormalities were classified as minor in 20 (13%; 95% CI 9-19%) and mildly abnormal in 17 (11%; 95% CI 7-17%). None of the infants showed severe abnormalities. The abnormalities were not associated with the duration or maximum amount of cocaine use during pregnancy.

Conclusion: None of the infants had severe abnormalities. Detected abnormalities were not correlated with the duration or maximum amount of cocaine use. Given these findings, we feel that routine cranial ultrasonography in this population is not warranted.

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References

    1. Epidemiol Rev. 1994;16(2):315-34 - PubMed
    1. Arch Dis Child Fetal Neonatal Ed. 2000 Mar;82(2):F128-33 - PubMed
    1. AJNR Am J Neuroradiol. 1994 Apr;15(4):697-702 - PubMed
    1. Ann N Y Acad Sci. 1998 Jun 21;846:40-50 - PubMed
    1. Pediatrics. 1999 Nov;104(5 Pt 1):1101-5 - PubMed

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