Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Mar;9(2):153-61.
doi: 10.1016/j.meegid.2008.11.005. Epub 2008 Nov 28.

Understanding the molecular epidemiology of foot-and-mouth-disease virus

Joern Klein  1
Affiliations
Review

Understanding the molecular epidemiology of foot-and-mouth-disease virus

Joern Klein. Infect Genet Evol. 2009 Mar.

Abstract

The use of molecular epidemiology is an important tool in understanding and consequently controlling FMDV. In this review I will present basic information about the disease, needed to perform molecular epidemiology. I will give a short introduction to the history and impact of foot-and-mouth disease, clinical picture, infection route, subclinical and persistent infections, general aspects of the transmission of FMDV, serotype-specific epidemiological characteristics, field epidemiology of FMDV, evolution and molecular epidemiology of FMDV. This is followed by two chapters describing the molecular epidemiology of foot-and-mouth disease in global surveillance and molecular epidemiology of foot-and-mouth disease in outbreak investigation.

PubMed Disclaimer

References

    1. Aidaros H.A. Regional status and approaches to control and eradication of foot and mouth disease in the Middle East and North Africa. Rev Sci Tech. 2002;21:451–458. - PubMed
    1. Alexandersen S., Brotherhood I., Donaldson A.I. Natural aerosol transmission of foot-and-mouth disease virus to pigs: minimal infectious dose for strain O1 Lausanne. Epidemiol Infect. 2002;128:301–312. - PMC - PubMed
    1. Alexandersen S., Donaldson A.I. Further studies to quantify the dose of natural aerosols of foot-and-mouth disease virus for pigs. Epidemiol Infect. 2002;128:313–323. - PMC - PubMed
    1. Alexandersen S., Kitching R.P., Mansley L.M., Donaldson A.I. Clinical and laboratory investigations of five outbreaks of foot-and-mouth disease during the 2001 epidemic in the United Kingdom. Vet Rec. 2003;152:489–496. - PubMed
    1. Alexandersen S., Mowat N. Foot-and-mouth disease: host range and pathogenesis. Curr Top Microbiol Immunol. 2005;288:9–42. - PubMed

MeSH terms

Substances

LinkOut - more resources