Comment
doi: 10.1016/j.immuni.2008.12.002.
Elite suppression of HIV-1 replication
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- PMID: 19100698
- DOI: 10.1016/j.immuni.2008.12.002
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Comment
Elite suppression of HIV-1 replication
Immunity.
.
Free article
Abstract
Rare HIV-1-infected individuals are able to control viral replication without antiretroviral therapy. In this issue of Immunity, Migueles et al. (2008) show that HIV-1-specific CD8+ T cells from these individuals effectively suppress viral replication by granzyme B-mediated killing of target cells.
Comment on
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Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control.Immunity. 2008 Dec 19;29(6):1009-21. doi: 10.1016/j.immuni.2008.10.010. Epub 2008 Dec 8. Immunity. 2008. PMID: 19062316 Free PMC article.
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