Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Mar;32(3):394-6.
doi: 10.2337/dc08-1622. Epub 2008 Dec 23.

Reduced 10-year risk of coronary heart disease in patients who participated in a community-based diabetes prevention program: the DEPLOY pilot study

Elaine R Lipscomb  1 , Emily A Finch, Edward Brizendine, Chandan K Saha, Laura M Hays, Ronald T Ackermann
Affiliations

Reduced 10-year risk of coronary heart disease in patients who participated in a community-based diabetes prevention program: the DEPLOY pilot study

Elaine R Lipscomb et al. Diabetes Care. 2009 Mar.

Abstract

Objective: We evaluated whether participation in a community-based group diabetes prevention program might lead to relative changes in composite 10-year coronary heart disease (CHD) risk for overweight adults with abnormal glucose metabolism.

Research design and methods: We used the UK Prospective Diabetes Study engine to estimate CHD risk for group-lifestyle and brief counseling (control) groups. Between-group risk changes after 4 and 12 months were compared using ANCOVA.

Results: Baseline 10-year risk was similar between treatment groups (P = 0.667). At 4 and 12 months, the intervention group experienced significant decreases in 10-year risk from baseline (-3.28%, P < 0.001; and -2.23%, P = 0.037) compared with control subjects (-0.78%, P = 0.339; and +1.88%, P = 0.073). Between-group differences were statistically significant and increased from the 4- to 12-month visits.

Conclusions: Community-based delivery of the Diabetes Prevention Program lifestyle intervention could be a promising strategy to prevent both CHD and type 2 diabetes in adults with pre-diabetes.

PubMed Disclaimer

References

    1. Benjamin SM, Valdez R, Geiss LS, Rolka DB, Narayan KM: Estimated number of adults with prediabetes in the U.S. in 2000: opportunities for prevention. Diabetes Care 26:645–649, 2003 - PubMed
    1. Haffner SM: Pre-diabetes, insulin resistance, inflammation and CVD risk. Diabetes Res Clin Pract 61(Suppl. 1):S9–S18, 2003 - PubMed
    1. Leiter LA: From hyperglycemia to the risk of cardiovascular disease. Rev Cardiovasc Med 7(Suppl. 2):S3–S9, 2006 - PubMed
    1. Ackermann RT, Finch EA, Brizendine E, Zhou H, Marrero DG: Translating the Diabetes Prevention Program into the community: the DEPLOY pilot study. Am J Prev Med 35:357–363, 2008 - PMC - PubMed
    1. American Diabetes Association: Diabetes dropout Risk Calculator [Internet], 2008. Available from http://www.diabetes.org/risk-test.jsp. Accessed 7 November 2008

Publication types