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. 2009 Mar;20(2):91-3.
doi: 10.1097/MCA.0b013e3283219e61.

Obstructive coronary artery disease in high-risk diabetic patients with and without atrial fibrillation

Bredy Pierre-Louis  1 , Wilbert S Aronow, Chandrasekar Palaniswamy, Tarunjit Singh, Melvin B Weiss, Kumar Kalapatapu, Anthony L Pucillo, Craig E Monsen
Affiliations

Obstructive coronary artery disease in high-risk diabetic patients with and without atrial fibrillation

Bredy Pierre-Louis et al. Coron Artery Dis. 2009 Mar.

Abstract

Objective: To investigate the severity of coronary artery disease by coronary angiography in age-matched and sex-matched patients with diabetes mellitus with atrial fibrillation versus sinus rhythm.

Methods: The patients included 245 men and women, mean age of 70 years, with diabetes and atrial fibrillation and 245 age-matched and sex-matched patients with diabetes and sinus rhythm who underwent coronary angiography. Baseline characteristics and indications for coronary angiography were similar in both groups.

Results: Greater than 50% narrowing of one, two, or three major coronary arteries were present in 229 of 245 patients (94%) with diabetes and atrial fibrillation and in 211 of 245 patients (86%) with diabetes and with sinus rhythm (P<0.01). Greater than 50% narrowing of three major coronary arteries were present in 150 of 245 patients (61%) with diabetes and atrial fibrillation and in 75 of 245 patients (31%) with diabetes and sinus rhythm (P<0.001).

Conclusion: Patients with diabetes and atrial fibrillation have a significantly higher prevalence of greater than 50% narrowing of one or more major coronary arteries and of three major coronary arteries than patients with diabetes and sinus rhythm.

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