Necroptosis: a specialized pathway of programmed necrosis
- PMID: 19109884
- DOI: 10.1016/j.cell.2008.12.004
Necroptosis: a specialized pathway of programmed necrosis
Abstract
Necrosis is often viewed as an accidental and unregulated cellular event. However, accumulating evidence suggests that necrosis, like apoptosis, can be executed by regulated mechanisms. Hitomi et al. (2008) now describe an extensive network of genes that mediate a form of programmed necrosis called necroptosis.
Comment on
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Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway.Cell. 2008 Dec 26;135(7):1311-23. doi: 10.1016/j.cell.2008.10.044. Cell. 2008. PMID: 19109899 Free PMC article.
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