doi: 10.1007/s10517-008-0111-9.
Effect of afobazole on teratogenic activity of cyclophosphamide in rats
Affiliations
- PMID: 19110587
- DOI: 10.1007/s10517-008-0111-9
Item in Clipboard
Effect of afobazole on teratogenic activity of cyclophosphamide in rats
Bull Exp Biol Med.
2008 Apr.
Abstract
A new anxiolytic afobazole (1-100 mg/kg perorally, Russia) dose-dependently abolished the embryotoxic and teratogenic effects of cyclophosphamide and reduced the range of induced malformations in outbred albino rats. Our results suggest that afobazole possesses antiteratogenic activity.
Similar articles
-
[Antimutagenic and antiteratogenic properties of afobazole].Eksp Klin Farmakol. 2009 Jan-Feb;72(1):46-51. Eksp Klin Farmakol. 2009. PMID: 19334511 Russian.
-
[Association of genotoxic and teratogenic effects induced by cyclophosphamide and their modification with afobazole].Gig Sanit. 2011 Sep-Oct;(5):64-8. Gig Sanit. 2011. PMID: 22185008 Russian.
-
[The antimutagenic activity of afobazol studied in vivo].Eksp Klin Farmakol. 2000 Mar-Apr;63(2):57-9. Eksp Klin Farmakol. 2000. PMID: 10834097 Russian.
-
Anxiolytic Properties of Trimetazidine in Experimental Models of Increased Anxiety.Bull Exp Biol Med. 2017 Mar;162(5):643-646. doi: 10.1007/s10517-017-3677-2. Epub 2017 Mar 31. Bull Exp Biol Med. 2017. PMID: 28361425
-
Evaluation of the teratogenic potential of chemicals in the rat.Pharmacology. 1990;40 Suppl 1:1-27. doi: 10.1159/000138688. Pharmacology. 1990. PMID: 2185494 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
