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. 2008 Apr;145(4):436-9.
doi: 10.1007/s10517-008-0111-9.

Effect of afobazole on teratogenic activity of cyclophosphamide in rats

O V Shreder  1 , N M Smolnikova, A D Durnev, S B Seredenin
Affiliations

Effect of afobazole on teratogenic activity of cyclophosphamide in rats

O V Shreder et al. Bull Exp Biol Med. 2008 Apr.

Abstract

A new anxiolytic afobazole (1-100 mg/kg perorally, Russia) dose-dependently abolished the embryotoxic and teratogenic effects of cyclophosphamide and reduced the range of induced malformations in outbred albino rats. Our results suggest that afobazole possesses antiteratogenic activity.

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