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. 2009 Jan;15(1):56-8.
doi: 10.3201/eid1501.080755.

Experimental infection of dogs with avian-origin canine influenza A virus (H3N2)

Daesub Song  1 , Chulseung Lee, Bokyu Kang, Kwonil Jung, Taehoon Oh, Hyekwon Kim, Bongkyun Park, Jinsik Oh
Affiliations

Experimental infection of dogs with avian-origin canine influenza A virus (H3N2)

Daesub Song et al. Emerg Infect Dis. 2009 Jan.

Abstract

Susceptible dogs were brought into contact with dogs experimentally infected with an avian-origin influenza A virus (H3N2) that had been isolated from a pet dog with severe respiratory syndrome. All the experimentally infected and contact-exposed dogs showed elevated rectal temperatures, virus shedding, seroconversion, and severe necrotizing tracheobronchitis and bronchioalveolitis.

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Figures

Figure 1
Figure 1
Histopathologic appearance of tissue of dogs experimentally exposed to canine influenza virus by contact with infected dogs. Severe necrotizing, suppurative tracheitis and bronchioalveolitis were observed in the contact-exposure group on day postinoculation (dpi) 13. However, influenza-associated lesions were not yet present in these dogs on dpi 7. Original magnification was ×200 for all images. Hematoxylin and eosin stain.
Figure 2
Figure 2
Virus shedding and serologic response of beagles after experimental contact transmission of canine influenza virus. EID, egg infectious dose; PI, percentage inhibition.
See this image and copyright information in PMC

References

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