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. 2009 Jan;15(1):79-82.
doi: 10.3201/eid1501.080264.

Enterovirus 71 outbreak, Brunei

Sazaly AbuBakar  1 , I-Ching Sam, Jaliha Yusof, Meng Keang Lim, Suzana Misbah, NorAziyah MatRahim, Poh-Sim Hooi
Affiliations

Enterovirus 71 outbreak, Brunei

Sazaly AbuBakar et al. Emerg Infect Dis. 2009 Jan.

Abstract

Enterovirus 71 (EV71) outbreaks occur periodically in the Asia-Pacific region. In 2006, Brunei reported its first major outbreak of EV71 infections, associated with fatalities from neurologic complications. Isolated EV71 strains formed a distinct lineage with low diversity within subgenogroup B5, suggesting recent introduction and rapid spread within Brunei.

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Figures

Figure
Figure
Phylogenetic relationships of enterovirus 71 partial viral protein (VP1) gene sequences. The prototype coxsackievirus A16 (CoxA16-G10) was used as the outgroup virus. The phylogenetic tree shown was constructed by using the neighbor-joining method. Bootstrap values (>95%) are shown as percentages derived from 1,000 samplings at the nodes of the tree. Scale bar denotes number of nucleotide substitutions per site along the branches. Isolates from this study are indicated by * (Brunei) and † (Peninsular Malaysia).
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