Models use leptin and calculus to count calories
- PMID: 19117539
- DOI: 10.1016/j.cmet.2008.12.006
Models use leptin and calculus to count calories
Abstract
Thermostats have "set-points" that engineers design with mathematical rigor. Work in this issue of Cell Metabolism (Tam et al., 2009) applies similar modeling strategies to explore the control of murine energy and body weight homeostasis by leptin.
Comment on
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A mathematical model of murine metabolic regulation by leptin: energy balance and defense of a stable body weight.Cell Metab. 2009 Jan 7;9(1):52-63. doi: 10.1016/j.cmet.2008.11.005. Cell Metab. 2009. PMID: 19117546 Free PMC article.
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