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Comment
. 2009 Jan;94(1):10-6.
doi: 10.3324/haematol.2008.001263.

Treatment of acute myeloid leukemia

Elihu H Estey  1
Affiliations
Comment

Treatment of acute myeloid leukemia

Elihu H Estey. Haematologica. 2009 Jan.

Abstract

The treatment of acute myeloid leukemia has improved in the last ten years, and in this perspective article Dr. Estey examines the recent progress in this field. See related articles on pages 54 and 102.

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Figures

Figure 1.
Figure 1.
Effect of response on survival. The analysis was limited to patients who lived at least 60 days from the start of induction therapy by which time more than 90% of patients who achieved a complete response and 75% of those who achieved a complete response with incomplete platelet recovery had done so. Results were similar if patients who died before day 35 (median time to complete response), day 90, etc. were excluded.
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Comment on

References

    1. Morra E, Barosi G, Bosi A, Ferrara F, Locatelli F, Marchetti M, et al. Clinical management of primary non-APL acute myeloid leukemia: practice Guidelines by the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation. Haematologica. 2009;94:102–12. - PMC - PubMed
    1. Schlenk RF, Dohner K, Kneba M, Gotze K, Hartmann F, Valle Fd, et al. Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia-results from the AMLSG trial AML HD98B. Haematologica. 2009;94:54–60. - PMC - PubMed
    1. Estey EH, Bedikian SH, Witter DC, Pierce SA, Giles FJ. The predictive value of a “Positive” ASH abstract in AML therapeutics. Blood. 2006;108 abstract#1964.
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    1. Estey E, Dohner H. Acute myeloid leukaemia. Lancet. 2006;368:1894–907. - PubMed

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