Inhibitors of hypoxanthine metabolism in Ehrlich ascites tumor cells in vitro
- PMID: 191189
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Inhibitors of hypoxanthine metabolism in Ehrlich ascites tumor cells in vitro
Cancer Treat Rep.
1976 Oct.
Abstract
One hundred and sixty-one purine analogs and derivatives were tested for their ability to inhibit ten parameters of purine metabolism in Ehrlich ascites tumor cells incubated in vitro with radioactive hypoxanthine. Sixty-seven compounds were inhibitory against at least one parameter and 30 were inhibitory against two or more.
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