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. 1976 Oct;60(10):1567-84.

Inhibitors of hypoxanthine metabolism in Ehrlich ascites tumor cells in vitro

C M Smith, G Zombor, J F Henderson
  • PMID: 191189

Inhibitors of hypoxanthine metabolism in Ehrlich ascites tumor cells in vitro

C M Smith et al. Cancer Treat Rep. 1976 Oct.

Abstract

One hundred and sixty-one purine analogs and derivatives were tested for their ability to inhibit ten parameters of purine metabolism in Ehrlich ascites tumor cells incubated in vitro with radioactive hypoxanthine. Sixty-seven compounds were inhibitory against at least one parameter and 30 were inhibitory against two or more.

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